Estudio químico preliminar de raíz de Lasianthaea aurea

Abstract

In the present work, a preliminary phytochemical study of the hexanic extract from the roots of Lasianthaea aurea was carried out. This vegetal specie belongs to the Asteraceae family; it is considered an endemic plant from Mexico, growing abundantly in Michoacán State. Few species from this genus have been chemically studied; furthermore, from L. aurea no chemical study was described to date. In this preliminary chemical study the isolation and identification of the majority metabolites was possible; two diterpene compounds with the ent-kaurene skeleton type were identified as ent-kaur-16-en-19-oic acid (6) and 15-α-angeloyloxy-16α,17-epoxyent-kaur-16-en-19-oic acid (14). These compounds were characterized by its NMR data.

En el presente trabajo se llevó a cabo un estudio fitoquímico preliminar del extracto hexánico de raíz de Lasianthaea aurea, una especie que no ha sido explorada químicamente, endémica de México, y se encuentra abundantemente en Michoacán, esta especie forma parte de la extensa familia de las Asteraceas, y pertenece al género Lasianthaea, del cual existen muy pocos artículos que hablen de su investigación. Los compuestos mayoritarios aislados e identificados correspondieron a diterpenos de tipo kaureno: ácido ent-kaur-16-en-19-oico (6) y ácido 15-α-angeloiloxi-16α,17-epoxient-kaur-16-en-19-oico (14). Caracterizados por sus datos de RMN.