Aislamiento y caracterización de un monoterpeno glucosilado de Ageratina glabrata

Abstract

Ageratina glabrata belongs to the Asteraceae family and it is employed in traditional medicine as analgesic and antiiflammatory. In previous studies of this plant secondary metabolites have been isolated, mainly terpene compounds from lower polarity extracts of the aerial parts.The phytochemical study of methanolic extract from leaves of A. glabrata yielded the glucoside p-menthene 33 which was identifiedby its physical and spectroscopic data, and its peracetylated derivative 34 was prepared.

Ageratina glabrata pertenece a la familia Asteraceae y es reconocida en la medicina tradicional por presentar capacidad analgésica. En estudios químicos previos de esta planta se han aislado principalmente compuestos de naturaleza terpénica en extractos de baja polaridad de las partes aéreas. Al realizar el estudio fitoquímico del extracto metanólico de hojas de A. glabrata se aisló e identificó al glucósido de p-menteno 33 y se preparó su derivado peracetilado 34.