Browsing by Author "Pérez Aguilar, José Manuel"

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Análisis por dinámica molecular atomística de los cambios conformacionales del sitio activo de la proteasa principal Mpro de SARS-CoV-2, mediados por los inhibidores alostéricos RS-102895 y AT7519

Manríquez Lúa, Oriana Carey (Universidad Michoacana de San Nicolas de Hidalgo, 2024-08)

SARS-CoV-2 is a virus belonging to the Coronaviridae family, Betacoronavirus genus. During the SARS-CoV-2 replication cycle, the main protease Mpro plays a key role by generating a significant number of non-structural ...
Estudio del efecto de mutaciones puntuales del péptido IDR-1002 sobre la translocación al núcleo de la proteína Nrf2, utilizando métodos experimentales y computacionales

Romero Durán, Marco Antonio (Universidad Michoacana de San Nicolás de Hidalgo, 2021-05)

The transcription factor Nrf2 is essential to decrease the concentration of reactive oxygen species (ROS) produced in the inflammatory response caused by tissue damage, due to oxidative stress. The disrupt of interaction ...

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