Material and methods: Se I perform a descriptive, observational cross-sectional study conducted to adolescents aged 10 to 16, which included clinical history, measurement of TA, was somatometria, body composition and takes of glucose and insulin in fasting and postprandial, TGS, CL and HDL; variables were analyzed with statistical average +/-standard deviation with percentages and distribution with high-low percentile and teamed up with x 2 and compare averages with student T data were analysed in package SPSS version 15.0. Results: It included 146 patients, 69 Acanthosis nigricans and 77 without acanthosis nigricans between 10 and 16 years of age between May 2008 and June 2009, patients with Acanthosis nigricans, 47 patients presented obesity 22 did, 45 presented the insulin resistance and 24 had no insulin resistance while 49 patients had a glucose normal fasting 19 submitted 1 diabetes and pre-diabetes. In cholesterol and Trigliceridos values these were greater in adolescents with Acanthosis nigricans with respect to the of no Acanthosis, while HDL levels were higher in the latter group. Conclusions: Teens with Acanthosis nigricans is greater obesity related than those who do not have Acanthosis, there is greater risk in adolescents with Acanthosis nigricans develop resistance to insulin. Obesity in adolescents has a high ratio to develop resistance to insulin as well as alterations in lipids (cholesterol, triglycerides and HDL).
Identificar la relación acantosis nigricans con obesidad y resistencia a la insulina en adolescentes. Material y Métodos: Se realizó estudio descriptivo, observacional, transversal. Incluyó adolescentes de 10 a 16 años se les realizó Historia clínica, toma de TA, Somatometria, composición corporal, toma de glucosa e insulina en ayuno y postprandial, TGS, CL, y HDL; las variables se analizaron con estadística con media ± D.E., las variables de asociación se analizaron con x2 y se comparó promedios con t de Student. Resultados: Se incluyeron 146 pacientes, 69 con acantosis nigricans y 77 sin acantosis nigricans entre 10 y 16 años de edad entre mayo 2008 y junio 2009, con acantosis nigricans 47 presentaron obesidad y 22 no, 45 presentaron resistencia a la Insulina y 24 no presentaron RI, mientras que 49 tuvieron glucosa en ayuno normal, 19 presentaron prediabetes y 1 diabetes. Los valores de CL y TGS fueron mayores en los adolescentes con acantosis nigricans con respecto a los de sin acantosis, mientras que de HDL fueron mayores en este último grupo. Conclusiones: En adolescentes con acantosis nigricans hay mayor relación con obesidad que los que no presentan acantosis y existe mayor riesgo en adolescentes con acantosis nigricans de desarrollar RI. La obesidad en adolescentes tiene una alta relación para presentar RI así como alteraciones de lípidos (CL, TGS y HDL).
